Pakati pekukakavadzana pamusoro pezvekuwedzera, muyedzo wakaitwa muArgentina unopa zviratidzo zvinoenderana nezve basa re High kuchena omega-3 yehutano hwemoyo, ine mhedzisiro yakayerwa zvine mutsindo uye inoda maprotocol.
In chete Mavhiki e12, kutungamirirwa kwezuva nezuva kwe 2 magiramu emishonga EPA+DHA yakakwanisa kuderedza BP, kuderedza zviratidzo zvekuzvimba uye kugadzirisa elasticity yetsinga muvanhu vakuru vane hypertension uye dyslipidemia pasi pekurapa kwakagadzikana.
Muedzo weArgentina unopa data rakasimba pane omega-3
Chidzidzo chacho, chakanzi OMECARDIUM, yakagadzirwa se randomized, double-blind, placebo-controlled, nekubatanidzwa kwevanhu 130 vanorapwa kunzvimbo dzine mukurumbira. Iyo protocol yakasangana netsika uye yekutonga zviyero nemvumo kubva ANMAT uye komiti yakagamuchirwa.
Vazvipiri vakapihwa zvisina tsarukano placebo kana maviri 1 g capsules zuva nezuva yekuchena kwepamusoro omega-3 fatty acids (EPA: DHA chiyero padyo ne 1,2:1), yakawedzerwa kumushonga wavo wekutanga wehypertension uye lipids.
Kuongorora mhedzisiro, zviyero zvakatorwa pakutanga uye pakupedzisira: 24-awa ambulatory blood pressure monitoring (ABPM), central aortic pressure, vascular stiffness by carotid-femoral pulse wave velocity uye panel ye inflammatory biomarkers.
Zvabuda zvakaziviswa mukati misangano yepasi rose neyemuno yesainzi, uye vari kuburitswa mupepanhau rinoongororwa nevezera ravo, iro rinowedzera kuoneka uye chokwadi chekunze.
Chikwata chekutsvagisa chinosimbirira kuti omega-3 haitsivi iyo yakajairika pharmacological kurapwa, asi inogona kuita se mubatanidzwa zano mumaprofile akasarudzwa zvakanaka.
Zvavakayera uye kuchinja kwavakaona
Muboka rakatora omega-3, the 24-awa systolic pressure (yakayerwa neABPM) yakadzikira zvakanyanya kana ichienzaniswa ne placebo: -6,9 mmHg, zororo rinoderedza mutoro wehemodynamic pamwoyo.
Kudonha kwakaonekwawo mukati -6,6 mmHg in the pakati aortic pressure, shanduko yakanyatsoenderana nezviitiko zvakadai sekurwadziwa kwemoyo kana sitiroko, uye iyo inokosha pakuchengetedzwa kwetsinga huru.
Nezve arterial kuomarara, carotid-femoral pulse wave velocity yakadzikira −0,76 m/s, zvakaenzana nekamwe kuwedzera kwe 10% mu arterial elasticity, shanduko inowirirana nevascular "rejuvenation" munguva pfupi.
Zvicherechedzo zve kuzvimba akaperekedza maitiro aya: kuderedzwa kwakanyorwa mu neutrophil/lymphocyte ratio (-0,41), in the ferritin (−46,1 ng/mL) uye kuderera kwakangwara mu Ultrasensitive PCR (-0,37 mg/L). Mukufanana, hapana shanduko dzakakodzera dzakaonekwa mukati cholesterol kana triglycerides, zvinofanotaurwa kana uri kudzorwa nemishonga.
La kushivirira yaive yakakwira: mumwechete chete mutori wechikamu akashuma kusvotwa kwakakonzera kuregedzwa, pasina matambudziko makuru yakabatana nekuwedzera mune dzimwe nyaya.
Nzira yekuitora uye ndiani angabatsirwa nayo
Maererano nevanyori, zvakaonekwa zvikomborero zvinotsigira kushandiswa kwe Pharmaceutical omega-3 sekuwedzera mune varwere vane hypertension uye dyslipidemia ine chinoputika chikamu, nguva dzose mukati megadziriro yekurapa.
Izvo zvinokurudzirwa zvinovavarira kugadzirisa iyo dose maererano ne ngozi profile: mukudzivirira kwechipiri (nhoroondo yekurwadziwa kwemoyo kana sitiroko) inowanzoshandiswa 4g pazuva, nepo mune vanhu vasina zviitiko zvekare asi vane mwero / njodzi huru, vanotariswa 2-3 g / zuvaIyo hypothesis yekudzikisa dosi yeantihypertensive nekushandisa kwenguva refu inoramba yakavhurika kumwe kutsvakurudza.
Muhuwandu hwevanhu ne systolic pressure yakakura kupfuura 130 mmHg, kunyangwe pasina kuongororwa kwepamutemo kwehypertension, inogona kutariswa sechido, kunyangwe iyo nhungamiro haisati yaburitsa kurudziro yepasi rose mukudzivirira kwekutanga.
Nguva dzine zviratidzo zvakanakisisa mumabhuku dzinobva 3 kusvika 20 mwedzi, uye data yakareba yekutevera inodiwa kuti isimbise kusimba kwezvakaonekwa mhedzisiro.
Sekuchengetedza, zvinokurudzirwa kubvunza chiremba wako kana wemishonga usati watanga, kunyanya kana uri kutora. anticoagulants, nekuda kwezvinogona kuwedzera mhedzisiro pane coagulation; kana hove allergy, pane dzimwe nzira dzakadai algae mafuta.
Kusarudza kuwedzera kwehutano: mazano anoshanda
Tarisa kuti yakawanda sei chaiyo quantity ye EPA uye DHA inopa imwe neimwe dose: iyo yakanaka ndeyekutanga kubva ≥500 mg per capsule. Rangarira izvo 1.000 mg yemafuta ehove haina kuenzana ne1.000 mg ye omega-3.
Isa mberi mharidzo nenzira ye triglycerides chaiwo kana kuti reesterified, sezvo vachiwanzoratidza kunyura zviri nani zvichienzaniswa nemamwe mafomu emakemikari akaiswa.
El kurongedza kwakasviba inobatsira kuderedza oxidation; chigadzirwa chinofanira kuchengetwa kure nekupisa kunopisa uye shanduko yekushisa (zvakanakisa kunze kwekicheni kana yekugezera) kuchengetedza kutsva kwayo.
Tsvaga yakazvimiririra yekusimbisa zvisimbiso senge IFOS, iyo inopupurira kuchena (yakaderera mazinga e oxidation) uye kusavapo kwezvinosvibisa common (e.g. heavy metals). Kana usina chokwadi, bvunza wemishonga yako.
Kune avo vasingadyi hove, sarudzo dzinobva pane microalgae Ivo vanonyanya kupa DHA (uye, mune dzimwe nguva, zvakare EPA), ine njodzi yakaderera yekusachena sezvavanobva muzvirimwa zvinodzorwa; tarisa kuti capsule iri pasina gelatin kana iwe uchitsvaga vegan-inoshamwaridzika chigadzirwa.
Iyi itsva data set inoratidza kuti iyo mushonga giredhi omega-3 inogona kuwedzera kukosha kune akajairwa kurapwa mune varwere vane cardiometabolic njodzi, nguva dzose kutariswa nenyanzvi uye kusarudza zvigadzirwa zvemhando yepamusoro; zvidzidzo zvenguva refu zvakamirira kusimbisa kushingirira kwezvibatsiro uye kutsanangura zviri nani kuti ndiani anobatsira zvakanyanya.
